Women's Hormones & Natural Anti Aging | Special Report

Date: 10/01/1997    Written by: Jon Barron

Progesterone Creme & Hormonal Balancing

Every woman between the ages of 13 and 117 needs to seriously consider supplementation with a natural progesterone creme.

Why? Because virtually every woman who lives in an industrialized country (the United States, in particular) is at high risk of estrogen dominance because of exposure to xenoestrogens. Xeno- estrogens, which are mostly petroleum based synthetic estrogens, are now present in massive amounts in our food chain, water supply, and environment.

At one time, our diets afforded some protection. Fruits and grains and vegetables (in their natural state) provide low-action phytoestrogens for the body. These low-action estrogens fill the body's estrogen receptor sites -- making them unavailable for use by the more potent estrogens -- both natural and synthetic. Unfortunately, today's diets are dominated by processed foods, which are stripped of these beneficial phytoestrogens. The net result is that virtually all of the body's receptor sites are ready and waiting for the far more intense estrogens.

Some high potency estrogens (such as estrone and estradiol) are produced by the body itself. But far and away, the greatest problem comes from the powerful and destructive petrochemical-based xenoestrogens. Not only are these xenoestrogens omnipresent, they are considerably more potent than estrogen made by the ovaries -- some even potent in amounts as small as a billionth of a gram.

Before we proceed, it is important to understand what role estrogen plays in the body. In addition to promoting the growth of female characteristics at puberty, the estrogen hormones also promote cell growth. It is the estrogens, for example, that stimulate the buildup of tissue and blood in the uterus at the start of the menstrual cycle. The problem comes when high levels of estrogen (natural and synthetic) are unopposed by sufficient amounts of natural progesterone, which leads to continuous, unrestrained cell stimulation. Problems that can occur include:

  • Excess estrogen is the only known cause of endometrial cancer
  • Increased risk of breast cancer
  • Loss of bone mass
  • Increased risk of autoimmune disorders such as lupus
  • Fibrocystic breasts
  • Fibroid tumors
  • Depression and irritability
  • PMS symptoms such as cramping and bloating -- in addition to depression and irritability
  • Menopausal symptoms such as hot flashes and night sweats -- again, in addition to depression and irritability
  • Decreased sex drive
  • Increased body hair and thinning of scalp hair
  • Migraine headaches
  • Impaired thyroid function, including Grave's disease
  • Increased body fat
  • Increased blood clotting
  • Impaired blood sugar control
  • The astounding acceleration of puberty in young girls from an average age of 14 to 15, to now as young as 9 or 10. (This represents a speed up of as much as 1/3 sooner in their lives and has frightening implications for long term health.)
  • And, finally, xenoestrogens have been strongly implicated in declining male sperm production and the increase in the rates of testicular cancer and prostate cancer

The Answer: Balance Estrogen

The only natural balancer to excessive estrogen in the body is natural progesterone -- not more estrogen. But what about the synthetic "progesterones" (such as Provera) that your doctor recommends? Progesterone is a natural substance, and as such cannot be patented. The pharmaceutical companies, therefore, have to modify it slightly. They literally create a new molecule, called medroxyprogesterone -- that does not exist in nature -- in order to take out a patent. This "slightly" modified artificial progesterone is what most doctors prescribe. What effect does slight modification have?

Consider the fact that the testosterone molecule and the estrone molecule are virtually identical -- except for the fact that the positions of the oxygen atom and the OH atoms change places. This slight "modification," however, happens to be enough so that one hormone makes men...and the other women.




Even closer is the similarity between DHEA and estrone. The molecules are actually identical except for the location of some of the double bonds between carbon atoms. You cannot get closer. And yet the function of DHEA and estrone could not be more different.

And now look at the difference between natural progesterone and Provera:



The bottom line is that Provera is not natural. It's a synthetic form of progesterone that carries a whole range of serious side effects. A small sampling of these side effects, as listed in the Physician's Desk Reference, includes:

  • Depression
  • Birth defects
  • Increased body hair
  • Acne
  • Risk of embolism
  • Decreased glucose tolerance
  • And allergic reactions

Now, in exchange for these significant side effects, Provera does offer some protection against endometrial cancer and a very modest increase in bone formation.

On the other hand, supplementation with natural progesterone has NO known side effects. It is best utilized by the body when administered transdermally with a skin creme that contains approximately 500 milligrams per ounce of natural progesterone and offers the following potential health benefits

According to Dr. John R. Lee, the author of What Your Doctor May Not Tell You About Menopause, natural progesterone may significantly improve bone formation -- by as much as 15% - 35%. (Understand, this is unique to natural progesterone. Estrogen supplementation does not increase bone formation; it merely slows the rate of loss for a 5-year period around the time of menopause. And man-made progestin only mildly increases bone formation. If you are worried about osteoporosis, there is only one substance known that significantly improves bone formation -- and that's natural progesterone.)

  • Increased progesterone levels in the body may help to protect against endometrial cancer
  • They may also help protect against breast cancer
  • In addition, supplementation with natural progesterone can help relieve symptoms of PMS
  • Relieve symptoms of menopause
  • Normalize libido
  • Improve the body fat profile
  • Improve sleep patterns
  • And help relieve migraine headaches

The bottom line is that every woman living in the industrialized world should seriously consider supplementation with natural progesterone.

  • If you decide to begin a regimen of natural progesterone supplementation, look for a premium quality balancing creme that contains a minimum of 500 milligrams per ounce (the amount recommended by Dr. Lee) of 100% pure, USP grade progesterone, naturally derived from either wild yam or soybeans. Look for a natural vegetarian formula that uses no artificial or synthetically derived fragrances, parabens or preservatives. Look for a formula that uses all natural oils and an enhanced liposome delivery system to help move the progesterone through the skin. And finally, look for a formula that uses organic wild yam…if you can find it. It’s getting harder and harder to find companies that use it.

Whether you're still going through your menstrual cycles (or whether you're pre-menopausal, or menopausal, or post-menopausal), you need to seriously consider supplementation. The benefits are extraordinary; the risks virtually non-existent. And the risks of not supplementing potentially include: an increased risk of breast cancer, endometrial cancer, and osteoporosis -- to reiterate just a few. (And for men, natural progesterone can help with depression and can help relieve prostate problems.)

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    Submitted by BaselineFoundation on
    February 20, 2017 - 8:27pm

    They are two different things. The Women’s Formula works to balance out testosterone. A progesterone cream works to balance out exposure to chemical estrogens.

    Submitted by brian Rose on
    February 23, 2017 - 12:53pm
    Collingwood, Ontario ,


    After reading an some of your articles on Progesterone cream I tried to order some from your company for my grown daughter but discovered that you didn't carry it. I was told by baseline nutritionals to order it from a company called KOKORU. When she received the cream, this was written on the label
    ........MAY CAUSE CANCER...Can I get some explanation about this???

    Submitted by BaselineFoundation on
    February 24, 2017 - 9:43am

    Thank you State of California for unnecessarily spreading fear and uncertainty! This link will answer all your questions about progesterone crème in general and Kokoro in particular. http://balance-your-body-naturally.com/user/files/Prop65_ProgesteroneCancerWarning.pdf

    Incidentally, just for some perspective, every coffee shop in California posts the same warning. For more on the real story behind Prop 65, check out: https://jonbarron.org/dietary-supplements/attorney-general-war-against-supplements


    Submitted by Amanda on
    April 17, 2017 - 9:36am
    Wellington NZ ,

    I had a total hysterectomy at the age of 33 due to a couple of decades of continual ovarian cysts, miscarriages and a failed ivf treatment. The final cyst rupturing my remaining ovary and causing 300mls of free fluid to enter up into my right upper quadrant. After that I was put onto a femtran patch (50 which is just estrogen) weekly, due to not being able to tolerate Premarin orally (migraines etc)
    I also should mention that I had SLE diagnosed at the age of 23, although going by my past history the Dr presumed that I had it for at least 10 years, so have always struggled with chronic fatigue and the joint/muscle problems etc that go along with Systemic Lupus.
    Now aged 59, in the last 6 years I firstly had late onset type 1 diabetes diagnosed ..insulin dependant, hypothyroidism, hyponatremia which has been as low as 117, and fibromyalgia.
    I have absolutely zero energy now, and have been left with just what seems to be an ever increasing fatigue physically, mentally and emotionally. I seem to sleep more often than I'm awake and feel now that I have more in common with my 87 year old mother in law than my peers. Yes, I have had depression over the years, on and off but at present, have been feeling relatively steady for sometime. The only negative emotional feelings I have are of isolation, disappointment and utter frustration!
    Sorry about this being so long winded but I'm now wondering about progesterone and whether it may or may not help me return to the person that in some way resembles my former self, health wise and especially fitness and energy wise.
    Many thanks for hanging in there and kind regards to all.

    Submitted by BaselineFoundation on
    April 18, 2017 - 4:22pm

    For obvious legal reasons, we cannot diagnose or prescribe for specific medical conditions—merely provide information. With that in mind, you might want to reread the above article again as it should answer many of your questions. You also might want to read the section on immunomodulators in the following article https://jonbarron.org/blood-cleansing/anatomy-and-physiology-immune-system-part-4.

    Submitted by Jennifer Bell on
    August 20, 2017 - 1:40pm
    MARINA DEL REY , California

    I started having premenopause symptoms when I turned 46, a few months before my 47th birthday, I got new and some intense symptoms, like extreme dizziness, heart palpitations, anxiety attacks and severe nausea (like morning sickness), and migraines. I found a woman's forum that talked about Dr. Lee's book "What your doctor may not tell you about Premenopause" and it has made such a positive impact on my health. I take the cream daily and I do still have some symptoms but they are very minimal and liveable, when my pre menopause symptoms started I was so depressed because I thought what a horrible way to transition into this next part of my life but now I'm enjoying this transition.

    Submitted by PRISCILLA on
    February 10, 2019 - 12:44pm
    Ponoka ,

    What about Prometrium for progesterone?

    Submitted by Lisa Kelker on
    March 3, 2019 - 12:40pm
    Eugene , Oregon

    Please review Dr Lee ‘s original study. It is terribly flawed with no control group, most of the ladies were on estrogen, and his results are physiologically impossible. Many have tried and failed to reproduce his results.
    We do a disservice to our oatients and our reputations to keep using his debunked study.
    Natural P is wonderful for many things but the bone density information is totally wrong and dangerous. Estrogen and T increase bone density as well as DHEA.
    Do your own basic research sir, it won’t take you long at all. It’s a travesty that this falsehood has taken hold in our community


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